In healthy adult males the effects of YK-11 on muscle building quality are likely to be submaximal because it is a partial agonist on the androgen receptor and so a healthy male may experience reductions muscle strength and hardness while a female may experience improvements. However the ability of Yk-11 to increase follistatin levels compared to DHT and other steroids is what makes it novel. However no pre-clinical, clinical data exists to confirm its therapeutic significance if any.
No chemical compound to my knowledge exists that displays follistain stimulating effects like that of YK-11 so no comparison can be made. DHT is known to have effects on the CNS (central nervous system) and so YK-11 may also possess such effects if it can cross the blood brain barrier.
Because YK-11 is partial agonist to the androgen receptor it will be in direct competition with Test and DHT for binding and so its anabolic activity may be reliant on its ability to stimulate follistatin. Because of its partial agonist competition with Test and DHT it may reduce anabolic activity in otherwise healthy males. To date no safety data or animal testing exist.
YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it's as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.
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